PLOS ONE: MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells
![Sensitivity and Resistance of MET Exon 14 Mutations in Lung Cancer to Eight MET Tyrosine Kinase Inhibitors In Vitro - Journal of Thoracic Oncology Sensitivity and Resistance of MET Exon 14 Mutations in Lung Cancer to Eight MET Tyrosine Kinase Inhibitors In Vitro - Journal of Thoracic Oncology](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/85b4817c-8e1d-43df-8f10-f57239c512a8/gr1_lrg.jpg)
Sensitivity and Resistance of MET Exon 14 Mutations in Lung Cancer to Eight MET Tyrosine Kinase Inhibitors In Vitro - Journal of Thoracic Oncology
![The clinical efficacy of combinatorial therapy of EGFR-TKI and crizotinib in overcoming MET amplification-mediated resistance from prior EGFR-TKI therapy - Lung Cancer The clinical efficacy of combinatorial therapy of EGFR-TKI and crizotinib in overcoming MET amplification-mediated resistance from prior EGFR-TKI therapy - Lung Cancer](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/22912b0e-1d00-4f47-8887-774bdf471d82/gr1_lrg.jpg)
The clinical efficacy of combinatorial therapy of EGFR-TKI and crizotinib in overcoming MET amplification-mediated resistance from prior EGFR-TKI therapy - Lung Cancer
![Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer - Aguado - 2021 - Molecular Oncology - Wiley Online Library Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer - Aguado - 2021 - Molecular Oncology - Wiley Online Library](https://febs.onlinelibrary.wiley.com/cms/asset/1222194f-9a13-4155-8908-1458488c9299/mol212861-fig-0005-m.jpg)
Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer - Aguado - 2021 - Molecular Oncology - Wiley Online Library
![The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping - Cancer Treatment Reviews The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping - Cancer Treatment Reviews](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/2f846160-b4c3-44f1-82de-648c25ad83e0/gr1_lrg.jpg)
The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping - Cancer Treatment Reviews
![Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations | Scientific Reports Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-021-95985-6/MediaObjects/41598_2021_95985_Fig1_HTML.png)
Liquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations | Scientific Reports
![Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? | Semantic Scholar Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/d148502b7ecca9277cb2f13a735d6c2365bf99de/44-Figure1-1.png)
Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? | Semantic Scholar
![AXL/MET dual inhibitor, CB469, has activity in non-small cell lung cancer with acquired resistance to EGFR TKI with AXL or MET activation - Lung Cancer AXL/MET dual inhibitor, CB469, has activity in non-small cell lung cancer with acquired resistance to EGFR TKI with AXL or MET activation - Lung Cancer](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/a98bfb0a-1a30-492f-a180-5fc1433f14b7/gr1_lrg.jpg)
AXL/MET dual inhibitor, CB469, has activity in non-small cell lung cancer with acquired resistance to EGFR TKI with AXL or MET activation - Lung Cancer
![MET inhibitors for targeted therapy of EGFR TKI-resistant lung cancer | Journal of Hematology & Oncology | Full Text MET inhibitors for targeted therapy of EGFR TKI-resistant lung cancer | Journal of Hematology & Oncology | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13045-019-0759-9/MediaObjects/13045_2019_759_Fig5_HTML.png)
MET inhibitors for targeted therapy of EGFR TKI-resistant lung cancer | Journal of Hematology & Oncology | Full Text
PLOS ONE: MET Gene Amplification and MET Receptor Activation Are Not Sufficient to Predict Efficacy of Combined MET and EGFR Inhibitors in EGFR TKI-Resistant NSCLC Cells
![Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? - Cancer Treatment Reviews Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? - Cancer Treatment Reviews](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/914934b8-f430-470c-babf-a230a934ba6e/gr2_lrg.jpg)
Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? - Cancer Treatment Reviews
![1,2,4-Oxadiazole derivatives targeting EGFR and c-Met degradation in TKI resistant NSCLC - ScienceDirect 1,2,4-Oxadiazole derivatives targeting EGFR and c-Met degradation in TKI resistant NSCLC - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S022352341930741X-fx1.jpg)
1,2,4-Oxadiazole derivatives targeting EGFR and c-Met degradation in TKI resistant NSCLC - ScienceDirect
![JCM | Free Full-Text | The Role of MET Inhibitor Therapies in the Treatment of Advanced Non-Small Cell Lung Cancer | HTML JCM | Free Full-Text | The Role of MET Inhibitor Therapies in the Treatment of Advanced Non-Small Cell Lung Cancer | HTML](https://www.mdpi.com/jcm/jcm-09-01918/article_deploy/html/images/jcm-09-01918-g001.png)
JCM | Free Full-Text | The Role of MET Inhibitor Therapies in the Treatment of Advanced Non-Small Cell Lung Cancer | HTML
![Reciprocal relationship between MET amplification and T790M mutation.... | Download Scientific Diagram Reciprocal relationship between MET amplification and T790M mutation.... | Download Scientific Diagram](https://www.researchgate.net/profile/Isao-Murakami/publication/47729355/figure/fig2/AS:394319564427276@1471024518957/Reciprocal-relationship-between-MET-amplification-and-T790M-mutation-A-tumor-numbers.png)
Reciprocal relationship between MET amplification and T790M mutation.... | Download Scientific Diagram
![Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? - ScienceDirect Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0305737217301597-gr4.jpg)
Does c-Met remain a rational target for therapy in patients with EGFR TKI-resistant non-small cell lung cancer? - ScienceDirect
![MET inhibitors for targeted therapy of EGFR TKI-resistant lung cancer | Journal of Hematology & Oncology | Full Text MET inhibitors for targeted therapy of EGFR TKI-resistant lung cancer | Journal of Hematology & Oncology | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13045-019-0759-9/MediaObjects/13045_2019_759_Fig4_HTML.png)
MET inhibitors for targeted therapy of EGFR TKI-resistant lung cancer | Journal of Hematology & Oncology | Full Text
![Alterations in the PI3K Pathway Drive Resistance to MET Inhibitors in NSCLC Harboring MET Exon 14 Skipping Mutations - Journal of Thoracic Oncology Alterations in the PI3K Pathway Drive Resistance to MET Inhibitors in NSCLC Harboring MET Exon 14 Skipping Mutations - Journal of Thoracic Oncology](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/asset/e28be515-95b4-4f23-8f22-0ab2c845cb53/gr1.jpg)
Alterations in the PI3K Pathway Drive Resistance to MET Inhibitors in NSCLC Harboring MET Exon 14 Skipping Mutations - Journal of Thoracic Oncology
![PDF] EGFR and c-Met Inhibitors are Effective in Reducing Tumorigenicity in Cancer | Semantic Scholar PDF] EGFR and c-Met Inhibitors are Effective in Reducing Tumorigenicity in Cancer | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/fb34e0b378ab283ee885fb912c61cc28ae8a288b/3-Figure1-1.png)
PDF] EGFR and c-Met Inhibitors are Effective in Reducing Tumorigenicity in Cancer | Semantic Scholar
![Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre, open-label, phase 1b study - The Lancet Oncology Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre, open-label, phase 1b study - The Lancet Oncology](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/b1d3b867-74ab-4cf1-aad3-4997ae2f92eb/gr1.gif)